AN ATLAS OF ROBUST MICROBIOME ASSOCIATIONS WITH PHENOTYPIC TRAITS BASED ON LARGE-SCALE COHORTS FROM TWO CONTINENTS.

An atlas of robust microbiome associations with phenotypic traits based on large-scale cohorts from two continents.

Numerous human conditions are associated with the microbiome, yet studies are inconsistent as to the magnitude of the associations and the bacteria involved, likely reflecting insufficiently employed sample sizes.Here, we collected diverse phenotypes and gut microbiota from 34,057 individuals from Israel and the U.S.Analyzing these data using a muc

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Molecular Mechanisms of Hepatocarcinogenesis Following Sustained Virological Response in Patients with Chronic Hepatitis C Virus Infection

Despite the success of direct-acting antiviral (DAA) agents in treating chronic hepatitis C virus (HCV) infection, the number of cases of HCV-related hepatocellular carcinoma (HCC) is expected to increase over the next five years.HCC develops over the span of decades and is closely associated with fibrosis stage.HCV both directly and indirectly est

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